Research Journal of Pharmaceutical Dosage Form and Technology

V. S. Parmar ¹, S. C. Shivhare ¹

Affiliations
1 BM College of Pharmaceutical Education and Research, Indore, IN

Abstract

The first objective of this research was to develop a local application pharmaceutical formulation of a vaginal suppository with anti-microbial agent clotrimazole. The second objective was to establish a stable clotrimazole suppository and evaluation of suppository. In the present research a successful attempt to formulate a suppository by fusion method and the various evaluation parameters was done. The microbial test against the causative agents was performed. Finally the stability of the formulation was checked. The inhibitory action of the Clotrimazole suppository was satisfactorily. The methods of its evaluation developed in this research work may be beneficial in preventing bacterial vaginosis. Further investigations have to be carried out in antimicrobial activity in the bacterial viginosis treatment is needed.

Keywords

Vaginosis, Clotrimazole, Formulation, Microbial Test, Stability.

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S. C. Shivhare ¹, K. G. Malviya ², Vijay Jain ³, Guatam Negi ³

Affiliations
1 Sadar bazar B/H Ram Mandir, At post Paratwada, Dist Amravati (M.S) 444805, IN
2 MJRP College of Heath Care and Allied Science, MJRP University, Jaipur, IN
3 BM College of Pharmaceutical Education and Research, Indore(M.P), IN

Abstract

The purpose of this article is to serve as a beginners guide to what the Liposomes as a unique Novel Drug Delivery formulation and to briefly review. liposome's are tools for drug targeting in certain biomedical situations (e.g., cancer, HIV infection, gene therapy etc.) and for reducing the incidence of dose-related drug toxicity. Authors also tried to highlight the various Biomedical applications, Pharmacokinetics of Liposomes, types of liposome and industrial production method of liposomes.

Keywords

Liposomes, Pharmacokinetics, Types, Formulation.

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